• Adhesion dependent regulation of Aurora Kinase A and its role in RalA mediated anchorage-independence 

  Inchanalkar, Siddhi (2021-03-04)

  Integrin-mediated adhesion regulates membrane trafficking to control anchorage-dependent signaling and growth that is deregulated in cancers. Downstream of integrins and oncogenic Ras, the small GTPase Ral, is a vital ...
• Deciphering Structure-Functional Relationship of Heparan Sulfate using Iduronic Acid Glycans 

  Shanthamurthy, Chethan D. (2021-01-11)

  Heparan Sulfate (HS), a member of the glycosaminoglycan family, is composed of repeating units of α(1-4) linked D-glucosamine and uronic acid residues (L-iduronic acid and D-glucuronic acid) having diverse N-sulfation and ...
• Synthesis of Heterogeneous Heparan Sulfate Oligosaccharides to Investigate Structure- Activity Relationship (SAR) 

  Jain, Prashant (2021-02-16)

  Understanding the relationship between the chemical structure of a molecule and its biological activity holds tremendous potential for drug candidates’ development in several pathophysiological conditions. Carbohydrates, ...
• Isomerism-Activity Relation in Molecular Electrocatalysis and Molecular Charge Storage 

  Kottaichamy, Alagar Raja (2020-12)

  Electrocatalysts play major roles in energy conversion/storage, electrochemical sensing, environmental remediation, green chemistry, etc.; which in turn are responsible for the exhaustive attempts in understanding their ...
• First principles investigations of layered materials and their interaction with support 

  Joshi, Niharika (2020-04)

  Layered materials form an interesting class of materials wherein, atoms within the plane of the material interacts amongst themselves with strong covalent bonds, while along the direction normal to the plane, the interaction ...
• Applications of NMR-based Metabolomics: from cells to human body fluids to food 

  Yousf, Saleem (2021-01-22)

  Living organisms possess the ability to tune themselves in response to various Intra and extracellular cues, which in turn creates an assortment of metabolites in the cellular soup. Metabolomics – the science that deals ...
• Automorphic Forms and L-functions for Symplectic Groups of Genus 3 

  Pal, Manidipa (2020-09-15)

  For the similitude symplectic group GSp_6 over a totally real number field F, we establish the meromorphic continuation of the standard L-function and the spin L-function which are Langlands L-functions associated to the ...
• Negative growth regulatory role of PTPN11/SHP2 in breast epithelial tumorigenesis. 

  Chakladar, Madhumita (2020-05-27)

  Drosophila model system has played a pivotal role in the identification of genes involved at all stages of tumorigenesis. An RNAi mediated screen of the Drosophila genome conducted in our laboratory identified putative ...
• Silylene: Application as an Alluring Ligand in Transition Metals and Catalysis 

  Parvin, Nasrina (2020-10-14)

  Silylenes, previously only known as fugitive and transient laboratory curiosities in the 1960s, are now one of the most laboriously investigated classes of compounds in modish chemistry. The discovery of the first ...
• C3 FUNCTIONALIZATION OF 2-OXINDOLE TOWARDS DRUGS AND NATURAL PRODUCTS USING METAL AND METAL-FREE APPROACHES 

  Bisht, Girish Singh (2020-10-21)

  Oxindole is an important scaffold in pharmaceutical drugs and natural products. These derivatives have received significant attention among synthetic chemists and biologists due to their broad range of synthetic applications ...
• Understanding molecular mechanisms of T-helper 17 differentiation 

  Shetty, Ankitha (2020-12)

  Pro-inflammatory Th17 cells are critical for mucosal immune responses and also have implications in development of autoimmune disorders. So far, Th17 regulatory networks have been investigated using mouse models, but the ...
• Interplay between spin, heat, and charge currents in strongly correlated systems 

  De, Avirup (2020-12-24)

  Understanding the interplay between spin, heat, and charge currents is of fundamental importance in the area of Spintronics, where the spin degree of freedom plays a crucial role. The interaction between spin and heat ...
• Surface Ligand Controlled Photophysics and Photopatterning with InP/ZnS Quantum Dots 

  Gayathri, Devatha (2019-11-06)

  In nature, interactions play an important role in dictating functions to systems - for example, H-bonding in DNA hybridization for carrying genetic information, and substrate-enzyme interactions resulting in efficient ...
• Understanding Amyotrophic Lateral Sclerosis Using the Drosophila Tripartite Synapse. 

  Tendulkar, Shweta (2020-08-04)

  Understanding Amyotrophic Lateral Sclerosis using the Drosophila Tripartite synapse. Shweta Tendulkar Amyotrophic Lateral Sclerosis (ALS) is a progressive motor neurodegenerative disorder in humans with the death of ...
• Anchoring Cu(II)-based Low-Dimensional S=1/2 Spin Lattices onto Functionalized Graphene 

  Gupta, Kriti (2020-11)

  Magnetic materials with spins restricted in low-dimensions provide an intriguing platform to study spin interactions. Coupled with geometric frustration (for example, Kagome lattice), long-range magnetic ordering is ...
• Synthesis and Characterization of Novel Low-valent Compounds of Main Group Elements: Application in Organic Transformations 

  Raut, Ravindra (2020-08-14)

  Though the intriguing properties of main group compounds are harvested in every aspect of chemistry, there is a lot of scope for developing main group chemistry. In low valent state main group elements can mimic the ...
• Encapsulation of Magnetic Oxides inside Carbon Nanotubes 

  Kapoor, Aakanksha (2020-07-07)

  Transition Metal Oxides (TMOs) are well-known to host a diverse range of exotic electronic and magnetic ground states. Carbon Nanotubes (CNT), on the other hand, possess exceptional electrical, thermal and mechanical ...
• Synthesis, Surface Engineering and Stability of CsPbX3 (X= Cl, Br, I) and BaZrS3 Perovskite Nanocrystals 

  Ravi, Vikash Kumar (2020-07-31)

  Colloidal CsPbX3 (X= Cl, Br, I) perovskite nanocrystals have emerged as a new class of optoelectronic material. One of the major challenges now is to improve their stability. One of the major emphasis of my thesis is to ...
• Analysis of cytoplasmic organization and compartmentalization in syncytial Drosophila embryo 

  Thukral, Sameer (2020-01)

  Syncytial nuclei found in fungi, plant endosperm, insect embryos and muscles maintain an autonomous 'nuclear-cytoplasmic region of influence', thereby generating compartments within a seemingly shared cytoplasm. Molecular ...
• Exploring Structural and Chemical Reactivity of γ-Amino Acids in the Design of Peptide Foldamers and Small Molecule Peptidomimetics 

  Veeresh, K (2020-11-20)

  The progress in the field of foldamers constructed from the unnatural amino acid building blocks revealed that the folding phenomenon is not restricted to proteins. The advancement in the foldamer research has opened doors ...

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